Tetrabutylammonium fluoride solution

1.0 M solution in THF, containing ca. 5% H2O

  • Product Code: 93682
  Alias:    Tetrabutylammonium fluoride; tetrabutylammonium fluoride, related CAS number: 22206-57-1, 87749-50-6
  CAS:    429-41-4
Molecular Weight: 261.46 g./mol Molecular Formula: C₁₆H₃₆FN
EC Number: MDL Number: MFCD00011747
Melting Point: 62-63 °C(lit.) Boiling Point:
Density: 0.953 g/mL at 25 °C Storage Condition: room temperature, dry
Product Description: Tetrabutylammonium fluoride solution is widely used in organic synthesis as a source of fluoride ions, particularly for desilylation reactions. It effectively removes silyl protecting groups from molecules, making it valuable in the synthesis of complex organic compounds, including pharmaceuticals and natural products. Additionally, it serves as a catalyst or reagent in various fluorination reactions, enabling the introduction of fluorine atoms into organic molecules, which is crucial in drug development due to the unique properties fluorine imparts. Its application extends to material science, where it is used in the preparation of silicon-based materials and surface modifications. The solution is also employed in analytical chemistry for sample preparation and derivatization processes.
Product Specification:
Test Specification
STRENGTHTITRATION 0.95-1.1
WATER BY KARL FISCHER 4 7%
APPEARANCE colorless to light yellow to light brown liquid
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
25.000 10-20 days ฿390.00
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100.000 10-20 days ฿1,040.00
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500.000 10-20 days ฿3,970.00
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2500.000 10-20 days ฿16,840.00
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10000.000 10-20 days ฿47,680.00
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Tetrabutylammonium fluoride solution
Tetrabutylammonium fluoride solution is widely used in organic synthesis as a source of fluoride ions, particularly for desilylation reactions. It effectively removes silyl protecting groups from molecules, making it valuable in the synthesis of complex organic compounds, including pharmaceuticals and natural products. Additionally, it serves as a catalyst or reagent in various fluorination reactions, enabling the introduction of fluorine atoms into organic molecules, which is crucial in drug development due to the unique properties fluorine imparts. Its application extends to material science, where it is used in the preparation of silicon-based materials and surface modifications. The solution is also employed in analytical chemistry for sample preparation and derivatization processes.
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