3-Maleimidopropiohydrazide Trifluoroacetate
≥98%
- Product Code: 94475
CAS:
359436-61-6
| Molecular Weight: | 297.19 g./mol | Molecular Formula: | C₇H₉N₃O₃C₂HF₃O₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD01863410 | |
| Melting Point: | 125-129°C | Boiling Point: | |
| Density: | Storage Condition: | -20°C |
Product Description:
Used extensively in bioconjugation chemistry, this compound serves as a key reagent for linking biomolecules, such as proteins or peptides, to other entities like drugs, dyes, or solid supports. Its maleimide group reacts selectively with thiol groups under mild conditions, making it ideal for creating stable thioether bonds. This property is particularly valuable in antibody-drug conjugates (ADCs), where it facilitates the attachment of cytotoxic agents to antibodies for targeted cancer therapy. Additionally, it is employed in the development of biosensors and diagnostic tools, enabling the precise immobilization of biomolecules onto surfaces. Its hydrazide moiety also allows for conjugation with aldehyde or ketone groups, expanding its utility in various bioconjugation strategies.
Product Specification:
| Test | Specification |
|---|---|
| APPEARANCE | White to Almost white powder to crystal |
| PURITY | 97.5-100 |
| Infrared spectrum | Conforms to Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | £110.82 |
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| 0.250 | 10-20 days | £223.91 |
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3-Maleimidopropiohydrazide Trifluoroacetate
Used extensively in bioconjugation chemistry, this compound serves as a key reagent for linking biomolecules, such as proteins or peptides, to other entities like drugs, dyes, or solid supports. Its maleimide group reacts selectively with thiol groups under mild conditions, making it ideal for creating stable thioether bonds. This property is particularly valuable in antibody-drug conjugates (ADCs), where it facilitates the attachment of cytotoxic agents to antibodies for targeted cancer therapy. Additionally, it is employed in the development of biosensors and diagnostic tools, enabling the precise immobilization of biomolecules onto surfaces. Its hydrazide moiety also allows for conjugation with aldehyde or ketone groups, expanding its utility in various bioconjugation strategies.
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