5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite
98%
- Product Code: 97203
CAS:
251647-55-9
| Molecular Weight: | 913.99 g./mol | Molecular Formula: | C₄₇H₆₀N₇O₁₀P |
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| Density: | Storage Condition: | 2-8℃ |
Product Description:
This compound is primarily used in the synthesis of oligonucleotides, particularly in the field of nucleic acid research and therapeutic development. It serves as a key building block in solid-phase oligonucleotide synthesis, enabling the incorporation of modified guanosine residues into DNA or RNA sequences. The 2'-O-(2-methoxyethyl) modification enhances the stability and nuclease resistance of the resulting oligonucleotides, making it valuable for applications in antisense technology and RNA-based therapeutics. Additionally, the DMT (dimethoxytrityl) group protects the 5'-hydroxy during synthesis, allowing for stepwise elongation of the oligonucleotide chain. Its application is critical in the development of gene silencing drugs, diagnostic probes, and other advanced molecular biology tools.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 1.000 | 10-20 days | ฿9,738.00 |
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5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite
This compound is primarily used in the synthesis of oligonucleotides, particularly in the field of nucleic acid research and therapeutic development. It serves as a key building block in solid-phase oligonucleotide synthesis, enabling the incorporation of modified guanosine residues into DNA or RNA sequences. The 2'-O-(2-methoxyethyl) modification enhances the stability and nuclease resistance of the resulting oligonucleotides, making it valuable for applications in antisense technology and RNA-based therapeutics. Additionally, the DMT (dimethoxytrityl) group protects the 5'-hydroxy during synthesis, allowing for stepwise elongation of the oligonucleotide chain. Its application is critical in the development of gene silencing drugs, diagnostic probes, and other advanced molecular biology tools.
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