Fmoc-HoArg(Pbf)-OH
97%
- Product Code: 97574
CAS:
1159680-21-3
| Molecular Weight: | 662.8 g./mol | Molecular Formula: | C₃₅H₄₂N₄O₇S |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD03093571 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | room temperature, dry |
Product Description:
This compound is widely used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). It serves as a protected amino acid derivative, where the Fmoc (9-fluorenylmethoxycarbonyl) group protects the amino group, and the Pbf (2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl) group protects the guanidine side chain of arginine. This protection ensures selective reactions during peptide chain assembly, preventing unwanted side reactions. After the peptide chain is constructed, the Fmoc and Pbf groups can be removed under specific conditions, revealing the free amino and guanidine groups. This makes it a crucial reagent for synthesizing peptides containing arginine residues, which are common in biologically active peptides and proteins. Its application is essential in pharmaceutical research, drug development, and the production of peptide-based therapeutics.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.250 | 10-20 days | ฿612.00 |
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| 1.000 | 10-20 days | ฿1,395.00 |
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Fmoc-HoArg(Pbf)-OH
This compound is widely used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). It serves as a protected amino acid derivative, where the Fmoc (9-fluorenylmethoxycarbonyl) group protects the amino group, and the Pbf (2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl) group protects the guanidine side chain of arginine. This protection ensures selective reactions during peptide chain assembly, preventing unwanted side reactions. After the peptide chain is constructed, the Fmoc and Pbf groups can be removed under specific conditions, revealing the free amino and guanidine groups. This makes it a crucial reagent for synthesizing peptides containing arginine residues, which are common in biologically active peptides and proteins. Its application is essential in pharmaceutical research, drug development, and the production of peptide-based therapeutics.
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