N-Succinyl-Ala-Phe-Lys 7-amido-4-methylcoumarin acetate salt
≥95% (TLC)
- Product Code: 99139
CAS:
117756-27-1
| Molecular Weight: | 681.73 g./mol | Molecular Formula: | C₃₂H₃₉N₅O₈C₂H₄O₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00151397 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | −20°C |
Product Description:
Used primarily in biochemical research, this compound serves as a substrate for proteolytic enzymes, particularly for studying the activity of proteases like cathepsin B. Its application is crucial in enzyme kinetics assays, where the release of 7-amido-4-methylcoumarin (AMC) upon enzymatic cleavage is monitored through fluorescence. This allows researchers to quantify enzyme activity and screen for potential inhibitors, aiding in drug discovery and the study of disease mechanisms. Additionally, it is employed in cell biology to investigate intracellular protease functions and their roles in processes such as apoptosis and protein degradation.
Product Specification:
| Test | Specification |
|---|---|
| APPEARANCE | White to Light Yellow Powder |
| PURITY | 94.5-100 |
| WATER | 0 6% |
| Solubility Color | Colorless to Light Yellow |
| Solubility Turbidity | 50 mg/mL, 1M NH4OH,Clear to Slightly Hazy |
| Infrared spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 | 10-20 days | ฿13,600.00 |
+
-
|
N-Succinyl-Ala-Phe-Lys 7-amido-4-methylcoumarin acetate salt
Used primarily in biochemical research, this compound serves as a substrate for proteolytic enzymes, particularly for studying the activity of proteases like cathepsin B. Its application is crucial in enzyme kinetics assays, where the release of 7-amido-4-methylcoumarin (AMC) upon enzymatic cleavage is monitored through fluorescence. This allows researchers to quantify enzyme activity and screen for potential inhibitors, aiding in drug discovery and the study of disease mechanisms. Additionally, it is employed in cell biology to investigate intracellular protease functions and their roles in processes such as apoptosis and protein degradation.
| Mechanism | - |
| Appearance | - |
| Longevity | - |
| Strength | - |
| Storage | - |
| Shelf Life | - |
| Allergen(s) | - |
| Dosage (Range) | - |
| Recommended Dosage | - |
| Dosage (Per Day) | - |
| Recommended Dosage (Per Day) | - |
| Mix Method | - |
| Heat Resistance | - |
| Stable in pH range | - |
| Solubility | - |
| Product Types | - |
| INCI | - |
Cart
No products
Subtotal:
฿0.00
฿0.00
Total :