AHU-377 hemicalcium salt
≥99%
- Product Code: 99457
CAS:
1369773-39-6
| Molecular Weight: | 861.04 g./mol | Molecular Formula: | C₄₈H₅₆CaN₂O₁₀ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD28137893 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20℃ |
Product Description:
AHU-377 hemicalcium salt is primarily used in the development of pharmaceutical compounds, particularly in the treatment of cardiovascular diseases. It serves as a key intermediate in the synthesis of sacubitril, which is a component of the combination drug sacubitril/valsartan. This drug is widely prescribed for managing chronic heart failure with reduced ejection fraction. By inhibiting neprilysin, AHU-377 hemicalcium salt helps enhance the levels of beneficial peptides that promote vasodilation, reduce sodium retention, and improve overall cardiac function. Its role in this therapeutic application underscores its importance in advancing treatments for heart failure and improving patient outcomes.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 | 10-20 days | ฿792.00 |
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| 0.025 | 10-20 days | ฿1,845.00 |
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| 0.100 | 10-20 days | ฿3,690.00 |
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AHU-377 hemicalcium salt
AHU-377 hemicalcium salt is primarily used in the development of pharmaceutical compounds, particularly in the treatment of cardiovascular diseases. It serves as a key intermediate in the synthesis of sacubitril, which is a component of the combination drug sacubitril/valsartan. This drug is widely prescribed for managing chronic heart failure with reduced ejection fraction. By inhibiting neprilysin, AHU-377 hemicalcium salt helps enhance the levels of beneficial peptides that promote vasodilation, reduce sodium retention, and improve overall cardiac function. Its role in this therapeutic application underscores its importance in advancing treatments for heart failure and improving patient outcomes.
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