LY2228820
98%
- Product Code: 101338
CAS:
862507-23-1
| Molecular Weight: | 612.74 g./mol | Molecular Formula: | C₂₆H₃₇FN₆O₆S₂ |
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| EC Number: | MDL Number: | ||
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| Density: | Storage Condition: | -20°C |
Product Description:
LY2228820 is primarily investigated for its potential therapeutic applications in the field of oncology. It functions as a selective inhibitor of p38 MAPK (mitogen-activated protein kinase), a signaling pathway involved in cellular responses to stress and inflammation. By targeting this pathway, LY2228820 aims to disrupt the growth and survival of cancer cells, particularly in tumors where p38 MAPK activity is elevated. Research has explored its use in combination with other chemotherapeutic agents to enhance treatment efficacy, especially in resistant or aggressive cancers. Additionally, its role in modulating tumor microenvironment and reducing inflammation-related tumor progression is of significant interest in preclinical and clinical studies.
Product Specification:
| Test | Specification |
|---|---|
| Appearance | White To Off-White To Light Yellow To Yellow Powder Or Crystals |
| Purity (%) | 97.5-100 |
| Infrared Spectrum | Conforms To Structure |
| NMR | Conforms To Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 | 10-20 days | £149.82 |
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| 0.025 | 10-20 days | £590.10 |
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LY2228820
LY2228820 is primarily investigated for its potential therapeutic applications in the field of oncology. It functions as a selective inhibitor of p38 MAPK (mitogen-activated protein kinase), a signaling pathway involved in cellular responses to stress and inflammation. By targeting this pathway, LY2228820 aims to disrupt the growth and survival of cancer cells, particularly in tumors where p38 MAPK activity is elevated. Research has explored its use in combination with other chemotherapeutic agents to enhance treatment efficacy, especially in resistant or aggressive cancers. Additionally, its role in modulating tumor microenvironment and reducing inflammation-related tumor progression is of significant interest in preclinical and clinical studies.
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