Fmoc-Val-Cit-PAB-PNP
98%
- Product Code: 105918
CAS:
863971-53-3
| Molecular Weight: | 766.8 g./mol | Molecular Formula: | C₄₀H₄₂N₆O₁₀ |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C |
Product Description:
Used primarily in the field of peptide synthesis and drug development, this compound serves as a key intermediate in the creation of antibody-drug conjugates (ADCs). Its structure includes a self-immolative linker, which is crucial for the controlled release of cytotoxic agents in targeted cancer therapies. The Fmoc group protects the amino acid during synthesis, while the PNP ester facilitates coupling reactions. This chemical is particularly valuable in designing prodrugs that enhance the specificity and efficacy of cancer treatments by delivering potent drugs directly to tumor cells, minimizing damage to healthy tissues. Its application is pivotal in advancing precision medicine and improving therapeutic outcomes.
Product Specification:
| Test | Specification |
|---|---|
| Appearance | White To Light Yellow To Yellow To Brown Powder Or Crystals |
| Purity (%) | 97.5-100 |
| Infrared Spectrum | Conforms To Structure |
| NMR | Conforms To Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.050 | 10-20 days | Ft38,786.79 |
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| 0.250 | 10-20 days | Ft97,182.45 |
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| 1.000 | 10-20 days | Ft344,771.46 |
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Fmoc-Val-Cit-PAB-PNP
Used primarily in the field of peptide synthesis and drug development, this compound serves as a key intermediate in the creation of antibody-drug conjugates (ADCs). Its structure includes a self-immolative linker, which is crucial for the controlled release of cytotoxic agents in targeted cancer therapies. The Fmoc group protects the amino acid during synthesis, while the PNP ester facilitates coupling reactions. This chemical is particularly valuable in designing prodrugs that enhance the specificity and efficacy of cancer treatments by delivering potent drugs directly to tumor cells, minimizing damage to healthy tissues. Its application is pivotal in advancing precision medicine and improving therapeutic outcomes.
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| Stable in pH range | - |
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