PROTAC K-Ras Degrader-1
98%
- Product Code: 106398
CAS:
2378258-52-5
| Molecular Weight: | 999.12 g./mol | Molecular Formula: | C₅₃H₆₂N₁₀O₁₀ |
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| Density: | Storage Condition: | -20°C |
Product Description:
PROTAC K-Ras Degrader-1 is primarily used in cancer research to target and degrade the K-Ras protein, which is often mutated in various cancers. Its application lies in its ability to selectively bind to K-Ras and recruit an E3 ubiquitin ligase, leading to the protein's ubiquitination and subsequent degradation by the proteasome. This approach is particularly valuable in studying K-Ras-driven cancers, such as pancreatic, lung, and colorectal cancers, where traditional inhibitors have shown limited efficacy. By degrading K-Ras, it offers a potential therapeutic strategy to inhibit oncogenic signaling pathways and suppress tumor growth. Additionally, it serves as a tool for understanding the role of K-Ras in cellular processes and drug resistance mechanisms.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.001 | 10-20 days | $2,116.53 |
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| 0.005 | 10-20 days | $5,804.52 |
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PROTAC K-Ras Degrader-1
PROTAC K-Ras Degrader-1 is primarily used in cancer research to target and degrade the K-Ras protein, which is often mutated in various cancers. Its application lies in its ability to selectively bind to K-Ras and recruit an E3 ubiquitin ligase, leading to the protein's ubiquitination and subsequent degradation by the proteasome. This approach is particularly valuable in studying K-Ras-driven cancers, such as pancreatic, lung, and colorectal cancers, where traditional inhibitors have shown limited efficacy. By degrading K-Ras, it offers a potential therapeutic strategy to inhibit oncogenic signaling pathways and suppress tumor growth. Additionally, it serves as a tool for understanding the role of K-Ras in cellular processes and drug resistance mechanisms.
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