CLP257
≥98%(HPLC)
- Product Code: 121129
CAS:
1181081-71-9
| Molecular Weight: | 307.34 g./mol | Molecular Formula: | C₁₄H₁₄FN₃O₂S |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD28166488 | |
| Melting Point: | Boiling Point: | ||
| Density: | 1.50±0.1 g/cm3 | Storage Condition: | 2-8°C |
Product Description:
CLP257 is primarily investigated for its potential therapeutic applications in the field of neuroscience. It functions as a positive allosteric modulator of the KCC2 transporter, which plays a critical role in regulating chloride ion homeostasis in neurons. By enhancing KCC2 activity, CLP257 has shown promise in restoring normal neuronal function in conditions characterized by impaired chloride transport, such as epilepsy, neuropathic pain, and certain psychiatric disorders. Preclinical studies suggest that it may help alleviate hyperexcitability in neural circuits, making it a candidate for developing treatments for these conditions. However, further research is needed to fully understand its efficacy and safety in clinical settings.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 | 10-20 days | €248.12 |
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CLP257
CLP257 is primarily investigated for its potential therapeutic applications in the field of neuroscience. It functions as a positive allosteric modulator of the KCC2 transporter, which plays a critical role in regulating chloride ion homeostasis in neurons. By enhancing KCC2 activity, CLP257 has shown promise in restoring normal neuronal function in conditions characterized by impaired chloride transport, such as epilepsy, neuropathic pain, and certain psychiatric disorders. Preclinical studies suggest that it may help alleviate hyperexcitability in neural circuits, making it a candidate for developing treatments for these conditions. However, further research is needed to fully understand its efficacy and safety in clinical settings.
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