tert-Butyl 3,3-difluoro-4-formylpiperidine-1-carboxylate

97%

  • Product Code: 131306
  CAS:    1373503-65-1
Molecular Weight: 249.25 g./mol Molecular Formula: C₁₁H₁₇F₂NO₃
EC Number: MDL Number: MFCD22199367
Melting Point: Boiling Point:
Density: Storage Condition: -20°C, Sealed, Inert Gas
Product Description: Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of fluorinated drug candidates. The aldehyde group allows for further functionalization through reactions such as reductive amination or Wittig reactions, enabling the construction of complex molecular architectures. The tert-butyl carbamate (Boc) group provides amine protection during multi-step syntheses, ensuring selective reactivity. Its piperidine core with geminal difluoro substitution enhances metabolic stability and membrane permeability in bioactive molecules, making it valuable in medicinal chemistry for CNS-targeted drugs and enzyme inhibitors.
Sizes / Availability / Pricing:
Size Availability Price Quantity
0.100 10-20 days Ft202,752.93
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-
0.250 10-20 days Ft328,566.95
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-
tert-Butyl 3,3-difluoro-4-formylpiperidine-1-carboxylate
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of fluorinated drug candidates. The aldehyde group allows for further functionalization through reactions such as reductive amination or Wittig reactions, enabling the construction of complex molecular architectures. The tert-butyl carbamate (Boc) group provides amine protection during multi-step syntheses, ensuring selective reactivity. Its piperidine core with geminal difluoro substitution enhances metabolic stability and membrane permeability in bioactive molecules, making it valuable in medicinal chemistry for CNS-targeted drugs and enzyme inhibitors.
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