Besifovir (LB80331)
10mM in DMSO
- Product Code: 142762
CAS:
441785-25-7
| Molecular Weight: | 299.22 g./mol | Molecular Formula: | C₁₀H₁₄N₅O₄P |
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| Density: | Storage Condition: | -20°C |
Product Description:
Besifovir is primarily used in the treatment of chronic hepatitis B virus (HBV) infection. It functions as a nucleotide analog that inhibits viral DNA synthesis by targeting the HBV polymerase enzyme, thereby suppressing viral replication. Due to its high potency and favorable resistance profile, it offers a therapeutic option for patients who may not respond well to other antiviral agents. Besifovir has shown improved renal safety compared to older antivirals, making it suitable for long-term administration. It is under clinical development and has demonstrated effective reduction of HBV DNA levels in serum, with potential for use in both HBeAg-positive and HBeAg-negative chronic hepatitis B patients.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | $438.35 |
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Besifovir (LB80331)
Besifovir is primarily used in the treatment of chronic hepatitis B virus (HBV) infection. It functions as a nucleotide analog that inhibits viral DNA synthesis by targeting the HBV polymerase enzyme, thereby suppressing viral replication. Due to its high potency and favorable resistance profile, it offers a therapeutic option for patients who may not respond well to other antiviral agents. Besifovir has shown improved renal safety compared to older antivirals, making it suitable for long-term administration. It is under clinical development and has demonstrated effective reduction of HBV DNA levels in serum, with potential for use in both HBeAg-positive and HBeAg-negative chronic hepatitis B patients.
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