tert-Butyl 3-(4-bromo-1H-pyrazol-1-yl)azetidine-1-carboxylate

98%

  • Product Code: 149825
  CAS:    877399-34-3
Molecular Weight: 302.17 g./mol Molecular Formula: C₁₁H₁₆BrN₃O₂
EC Number: MDL Number: MFCD17480368
Melting Point: Boiling Point:
Density: Storage Condition: 2-8°C
Product Description: Used as an intermediate in pharmaceutical synthesis, particularly in the development of kinase inhibitors and other biologically active compounds. The presence of the bromo-substituted pyrazole ring allows for further functionalization via cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, enabling the construction of complex molecular architectures. The tert-butoxycarbonyl (Boc) protecting group on the azetidine nitrogen ensures stability and selective deprotection under mild acidic conditions, making it valuable in multi-step synthetic routes. Commonly employed in medicinal chemistry for optimizing drug candidates targeting inflammatory, oncological, and central nervous system disorders.
Sizes / Availability / Pricing:
Size Availability Price Quantity
0.100 10-20 days $34.05
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0.250 10-20 days $74.05
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1.000 10-20 days $237.98
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5.000 10-20 days $755.51
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tert-Butyl 3-(4-bromo-1H-pyrazol-1-yl)azetidine-1-carboxylate
Used as an intermediate in pharmaceutical synthesis, particularly in the development of kinase inhibitors and other biologically active compounds. The presence of the bromo-substituted pyrazole ring allows for further functionalization via cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, enabling the construction of complex molecular architectures. The tert-butoxycarbonyl (Boc) protecting group on the azetidine nitrogen ensures stability and selective deprotection under mild acidic conditions, making it valuable in multi-step synthetic routes. Commonly employed in medicinal chemistry for optimizing drug candidates targeting inflammatory, oncological, and central nervous system disorders.
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