1-Boc-4-cyano-2,2-dimethyl-3-oxopyrrolidine
95%
- Product Code: 149856
CAS:
718632-42-9
| Molecular Weight: | 238.3 g./mol | Molecular Formula: | C₁₂H₁₈N₂O₃ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD08275049 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C, dry, closed |
Product Description:
Used in pharmaceutical synthesis as a key intermediate for constructing complex heterocyclic compounds, particularly in the development of bioactive molecules and drug candidates. Its protected amine group (Boc) allows selective reactivity, while the cyano and ketone functionalities enable further transformations such as reductions, nucleophilic additions, and cyclization reactions. Commonly employed in the synthesis of protease inhibitors and other therapeutic agents where pyrrolidine scaffolds are structural motifs. The presence of geminal dimethyl groups enhances steric stability and influences conformational rigidity in the final active compound.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | $397.38 |
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| 0.250 | 10-20 days | $674.55 |
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| 1.000 | 10-20 days | $2,233.49 |
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1-Boc-4-cyano-2,2-dimethyl-3-oxopyrrolidine
Used in pharmaceutical synthesis as a key intermediate for constructing complex heterocyclic compounds, particularly in the development of bioactive molecules and drug candidates. Its protected amine group (Boc) allows selective reactivity, while the cyano and ketone functionalities enable further transformations such as reductions, nucleophilic additions, and cyclization reactions. Commonly employed in the synthesis of protease inhibitors and other therapeutic agents where pyrrolidine scaffolds are structural motifs. The presence of geminal dimethyl groups enhances steric stability and influences conformational rigidity in the final active compound.
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