BMS-986299
98%
- Product Code: 151390
CAS:
2242952-69-6
| Molecular Weight: | 349.39 g./mol | Molecular Formula: | C₁₈H₁₉N₇O |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | Room temperature |
Product Description:
Used in clinical research for the treatment of advanced solid tumors, particularly in studies involving immune-oncology. It functions as a selective adenosine A2A receptor antagonist, helping to enhance anti-tumor immune responses by blocking immunosuppressive signals in the tumor microenvironment. Currently investigated in phase 1 and phase 2 trials, often in combination with other immunotherapies like PD-1 inhibitors, to improve outcomes in cancers such as non-small cell lung cancer and melanoma. Its development aims to overcome resistance to existing immunotherapies and boost T-cell activation against tumors.
Product Specification:
| Test | Specification |
|---|---|
| Appearance | White to Off-White Solid |
| Purity (%) | 97.5-100 |
| Mass Spectrum | Conforms to Structure |
| Infrared Spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 | 10-20 days | €308.81 |
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| 0.025 | 10-20 days | €902.54 |
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| 0.100 | 10-20 days | €2,303.74 |
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BMS-986299
Used in clinical research for the treatment of advanced solid tumors, particularly in studies involving immune-oncology. It functions as a selective adenosine A2A receptor antagonist, helping to enhance anti-tumor immune responses by blocking immunosuppressive signals in the tumor microenvironment. Currently investigated in phase 1 and phase 2 trials, often in combination with other immunotherapies like PD-1 inhibitors, to improve outcomes in cancers such as non-small cell lung cancer and melanoma. Its development aims to overcome resistance to existing immunotherapies and boost T-cell activation against tumors.
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| Heat Resistance | - |
| Stable in pH range | - |
| Solubility | - |
| Product Types | - |
| INCI | - |
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