1-(Bromomethyl)bicyclo[1.1.1]pentane
98%
- Product Code: 152073
CAS:
161043-38-5
| Molecular Weight: | 161.04 g./mol | Molecular Formula: | C₆H₉Br |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD20633000 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C, dry |
Product Description:
Used as a key reagent in medicinal chemistry for bioisosteric replacement of tert-butyl or alkyne groups. Its strained bridgehead structure enables efficient incorporation of the bicyclo[1.1.1]pentane (BCP) motif into drug candidates, serving as a stable, three-dimensional spacer that improves metabolic stability, solubility, and binding selectivity. Commonly employed in late-stage functionalization via nucleophilic substitution or cross-coupling reactions to introduce the BCP unit into complex molecules. Widely applied in the development of CNS drugs, agrochemicals, and PET tracers due to its favorable physicochemical properties and ability to modulate pharmacokinetics.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.025 | 10-20 days | $839.13 |
+
-
|
| 0.050 | 10-20 days | $1,282.17 |
+
-
|
| 0.100 | 10-20 days | $2,043.50 |
+
-
|
| 0.250 | 10-20 days | $4,121.15 |
+
-
|
1-(Bromomethyl)bicyclo[1.1.1]pentane
Used as a key reagent in medicinal chemistry for bioisosteric replacement of tert-butyl or alkyne groups. Its strained bridgehead structure enables efficient incorporation of the bicyclo[1.1.1]pentane (BCP) motif into drug candidates, serving as a stable, three-dimensional spacer that improves metabolic stability, solubility, and binding selectivity. Commonly employed in late-stage functionalization via nucleophilic substitution or cross-coupling reactions to introduce the BCP unit into complex molecules. Widely applied in the development of CNS drugs, agrochemicals, and PET tracers due to its favorable physicochemical properties and ability to modulate pharmacokinetics.
| Mechanism | - |
| Appearance | - |
| Longevity | - |
| Strength | - |
| Storage | - |
| Shelf Life | - |
| Allergen(s) | - |
| Dosage (Range) | - |
| Recommended Dosage | - |
| Dosage (Per Day) | - |
| Recommended Dosage (Per Day) | - |
| Mix Method | - |
| Heat Resistance | - |
| Stable in pH range | - |
| Solubility | - |
| Product Types | - |
| INCI | - |
Purchase History for
Loading purchase history...
Cart
No products
Subtotal:
$0.00
$0.00
Total :