Ethyl 2-(2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetate
98%
- Product Code: 184994
CAS:
1351500-37-2
| Molecular Weight: | 308.15 g./mol | Molecular Formula: | C₁₆H₂₂BFO₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD22381130 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | Room temperature, sealed |
Product Description:
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of complex organic molecules, particularly in pharmaceutical and agrochemical research. Its boronate ester group enables efficient carbon-carbon bond formation with aryl or vinyl halides under palladium catalysis. The ethyl ester functionality allows further transformation, such as hydrolysis to carboxylic acids or use in peptide-like coupling reactions. Commonly employed in the development of fluorinated biaryl compounds, which are important scaffolds in drug discovery due to enhanced metabolic stability and bioavailability. Also utilized in materials science for constructing conjugated systems in organic electronics.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
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| 0.100 | 10-20 days | $83.39 |
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| 0.250 | 10-20 days | $135.72 |
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| 1.000 | 10-20 days | $365.04 |
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| 5.000 | 10-20 days | $1,277.63 |
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Ethyl 2-(2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetate
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of complex organic molecules, particularly in pharmaceutical and agrochemical research. Its boronate ester group enables efficient carbon-carbon bond formation with aryl or vinyl halides under palladium catalysis. The ethyl ester functionality allows further transformation, such as hydrolysis to carboxylic acids or use in peptide-like coupling reactions. Commonly employed in the development of fluorinated biaryl compounds, which are important scaffolds in drug discovery due to enhanced metabolic stability and bioavailability. Also utilized in materials science for constructing conjugated systems in organic electronics.
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