4-(1-Fmoc-Piperidin-4-yl)-butyric acid

95%

  • Product Code: 189346
  CAS:    885274-47-5
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Density: Storage Condition: 2-8°C
Product Description: Widely used in solid-phase peptide synthesis, this compound serves as a key building block for introducing functionalized piperidine moieties into peptide chains. Its Fmoc-protected amine allows for orthogonal protection strategies, enabling selective deprotection under mild basic conditions while maintaining integrity of other protecting groups. The carboxylic acid group facilitates coupling to resin supports or amino groups of growing peptide sequences. It is especially valuable in the synthesis of peptidomimetics and bioactive molecules where conformational constraint and improved metabolic stability are desired. Commonly employed in the development of pharmaceuticals and medicinal research compounds targeting CNS receptors and enzyme inhibitors.
Sizes / Availability / Pricing:
Size Availability Price Quantity
0.250 10-20 days €286.77
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0.100 10-20 days €142.06
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4-(1-Fmoc-Piperidin-4-yl)-butyric acid
Widely used in solid-phase peptide synthesis, this compound serves as a key building block for introducing functionalized piperidine moieties into peptide chains. Its Fmoc-protected amine allows for orthogonal protection strategies, enabling selective deprotection under mild basic conditions while maintaining integrity of other protecting groups. The carboxylic acid group facilitates coupling to resin supports or amino groups of growing peptide sequences. It is especially valuable in the synthesis of peptidomimetics and bioactive molecules where conformational constraint and improved metabolic stability are desired. Commonly employed in the development of pharmaceuticals and medicinal research compounds targeting CNS receptors and enzyme inhibitors.
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