N-(3-((2,4-Dioxo-3-propyl-3,4-dihydrothieno[3,2-d]pyrimidin-1(2H)-yl)methyl)phenyl)-2-phenylacetamide
95%
- Product Code: 215686
CAS:
2098776-03-3
| Molecular Weight: | 433.52 g./mol | Molecular Formula: | C₂₄H₂₃N₃O₃S |
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| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | 1.325±0.06 g/cm3(Predicted) | Storage Condition: | 2-8°C, sealed, dry |
Product Description:
Used in pharmaceutical research as a potent and selective inhibitor of dihydroorotate dehydrogenase (DHODH), this compound shows promise in the development of anti-inflammatory and immunomodulatory agents. It has been investigated for its potential in treating autoimmune diseases such as rheumatoid arthritis due to its ability to suppress lymphocyte proliferation. Additionally, its structural properties make it a candidate for optimizing drug candidates targeting mitochondrial enzymes involved in pyrimidine biosynthesis. Ongoing studies explore its efficacy in oncology, particularly in leukemia models, where DHODH inhibition disrupts cancer cell metabolism and proliferation.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
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| 0.005 | 10-20 days | £574.04 |
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| 0.010 | 10-20 days | £975.94 |
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| 0.025 | 10-20 days | £1,657.88 |
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| 0.050 | 10-20 days | £2,817.39 |
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N-(3-((2,4-Dioxo-3-propyl-3,4-dihydrothieno[3,2-d]pyrimidin-1(2H)-yl)methyl)phenyl)-2-phenylacetamide
Used in pharmaceutical research as a potent and selective inhibitor of dihydroorotate dehydrogenase (DHODH), this compound shows promise in the development of anti-inflammatory and immunomodulatory agents. It has been investigated for its potential in treating autoimmune diseases such as rheumatoid arthritis due to its ability to suppress lymphocyte proliferation. Additionally, its structural properties make it a candidate for optimizing drug candidates targeting mitochondrial enzymes involved in pyrimidine biosynthesis. Ongoing studies explore its efficacy in oncology, particularly in leukemia models, where DHODH inhibition disrupts cancer cell metabolism and proliferation.
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