(R)-2-(piperidin-3-yl)isoindoline-1,3-dione
98%
- Product Code: 229979
CAS:
886588-61-0
| Molecular Weight: | 266.72 g./mol | Molecular Formula: | C₁₃H₁₅ClN₂O₂ |
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| EC Number: | MDL Number: | MFCD09752972 | |
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| Density: | Storage Condition: | Room temperature |
Product Description:
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of targeted protein degraders such as PROTACs (proteolysis-targeting chimeras). Its structural features allow for effective linker attachment between an E3 ligase ligand and a target protein binder. Commonly employed in oncology research due to its ability to engage cereblon (CRBN), an E3 ubiquitin ligase, facilitating the degradation of disease-causing proteins. Also utilized in the design of small molecule therapeutics for immunomodulatory and anti-inflammatory applications. Its chiral piperidine core supports high selectivity and binding affinity in complex biological systems.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
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| 1.000 | 10-20 days | $354.14 |
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| 25.000 | 10-20 days | $2,906.01 |
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| 5.000 | 10-20 days | $968.67 |
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(R)-2-(piperidin-3-yl)isoindoline-1,3-dione
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of targeted protein degraders such as PROTACs (proteolysis-targeting chimeras). Its structural features allow for effective linker attachment between an E3 ligase ligand and a target protein binder. Commonly employed in oncology research due to its ability to engage cereblon (CRBN), an E3 ubiquitin ligase, facilitating the degradation of disease-causing proteins. Also utilized in the design of small molecule therapeutics for immunomodulatory and anti-inflammatory applications. Its chiral piperidine core supports high selectivity and binding affinity in complex biological systems.
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