(R)-N-Benzhydryl-2-(3-(3,5-Bis(Trifluoromethyl)Phenyl)Thioureido)-N,3,3-Trimethylbutanamide

97%

  • Product Code: 231576
  CAS:    2748618-19-9
Molecular Weight: 581.62 g./mol Molecular Formula: C₂₉H₂₉F₆N₃OS
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Density: Storage Condition: Room temperature
Product Description: Used as a key intermediate in the synthesis of orexin receptor antagonists, particularly in the development of pharmaceuticals for sleep disorders such as insomnia. Its structure enables high selectivity and binding affinity to orexin receptors, which regulate wakefulness. Due to its chiral purity, the (R)-enantiomer enhances efficacy and reduces off-target effects in final drug formulations. Commonly employed in late-stage functionalization during API synthesis, it supports improved pharmacokinetic properties in central nervous system-targeted therapeutics.
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Size Availability Price Quantity
0.100 10-20 days $232.10
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(R)-N-Benzhydryl-2-(3-(3,5-Bis(Trifluoromethyl)Phenyl)Thioureido)-N,3,3-Trimethylbutanamide
Used as a key intermediate in the synthesis of orexin receptor antagonists, particularly in the development of pharmaceuticals for sleep disorders such as insomnia. Its structure enables high selectivity and binding affinity to orexin receptors, which regulate wakefulness. Due to its chiral purity, the (R)-enantiomer enhances efficacy and reduces off-target effects in final drug formulations. Commonly employed in late-stage functionalization during API synthesis, it supports improved pharmacokinetic properties in central nervous system-targeted therapeutics.
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