(S)-2-(tert-Butoxycarbonylamino)-4,4-difluorobutanoic acid
97%
- Product Code: 236967
CAS:
467442-20-2
| Molecular Weight: | 239.22 g./mol | Molecular Formula: | C₉H₁₅F₂NO₄ |
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| Density: | Storage Condition: | 2-8°C, dry |
Product Description:
Used as a chiral building block in the synthesis of pharmaceutical intermediates, particularly in the development of fluorinated bioactive molecules. Its protected amine and carboxylic acid functionalities allow for selective peptide coupling and deprotection steps in multi-step organic syntheses. The presence of geminal difluoro groups enhances metabolic stability and lipophilicity in final drug compounds, making it valuable in medicinal chemistry for optimizing pharmacokinetic properties. Commonly employed in the preparation of enzyme inhibitors and receptor modulators where stereochemistry plays a critical role in biological activity.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | $408.43 |
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| 0.250 | 10-20 days | $657.75 |
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| 1.000 | 10-20 days | $1,700.52 |
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(S)-2-(tert-Butoxycarbonylamino)-4,4-difluorobutanoic acid
Used as a chiral building block in the synthesis of pharmaceutical intermediates, particularly in the development of fluorinated bioactive molecules. Its protected amine and carboxylic acid functionalities allow for selective peptide coupling and deprotection steps in multi-step organic syntheses. The presence of geminal difluoro groups enhances metabolic stability and lipophilicity in final drug compounds, making it valuable in medicinal chemistry for optimizing pharmacokinetic properties. Commonly employed in the preparation of enzyme inhibitors and receptor modulators where stereochemistry plays a critical role in biological activity.
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