(3aS,8aR)-2-(4-(Trifluoromethyl)pyridin-2-yl)-3a,8a-dihydro-8H-indeno[1,2-d]oxazole
97%, 99%e.e.
- Product Code: 237476
CAS:
2757082-23-6
| Molecular Weight: | 304.27 g./mol | Molecular Formula: | C₁₆H₁₁F₃N₂O |
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| Density: | Storage Condition: | 2-8°C, sealed, dry, inert gas |
Product Description:
Used as a key intermediate in the synthesis of selective kinase inhibitors, particularly in the development of anticancer agents. Its rigid oxazole-indeno scaffold enhances binding affinity to protein targets, improving potency and selectivity. Employed in medicinal chemistry for optimizing pharmacokinetic properties in drug candidates targeting tyrosine kinase and cyclin-dependent kinase pathways. Also applied in the preparation of fluorescent probes due to its stable heterocyclic structure and electron-withdrawing trifluoromethylpyridine group, which enhances photostability and signal detection in cellular imaging.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
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| 0.250 | 10-20 days | $616.05 |
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| 1.000 | 10-20 days | $2,225.53 |
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(3aS,8aR)-2-(4-(Trifluoromethyl)pyridin-2-yl)-3a,8a-dihydro-8H-indeno[1,2-d]oxazole
Used as a key intermediate in the synthesis of selective kinase inhibitors, particularly in the development of anticancer agents. Its rigid oxazole-indeno scaffold enhances binding affinity to protein targets, improving potency and selectivity. Employed in medicinal chemistry for optimizing pharmacokinetic properties in drug candidates targeting tyrosine kinase and cyclin-dependent kinase pathways. Also applied in the preparation of fluorescent probes due to its stable heterocyclic structure and electron-withdrawing trifluoromethylpyridine group, which enhances photostability and signal detection in cellular imaging.
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