Tert-butyl ((3R,5S)-5-(trifluoromethyl)piperidin-3-yl)carbamate
95%
- Product Code: 242615
CAS:
1523530-57-5
| Molecular Weight: | 268.28 g./mol | Molecular Formula: | C₁₁H₁₉F₃N₂O₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD23105832 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C, away from light, dry, sealed |
Product Description:
Used as a key chiral intermediate in the synthesis of biologically active pharmaceuticals, particularly in the development of central nervous system (CNS) agents and protease inhibitors. Its stereochemistry and trifluoromethyl group enhance binding selectivity and metabolic stability in drug candidates. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to its rigid piperidine scaffold and steric protection from the tert-butyl carbamate group, which also serves as a protected amine for stepwise synthesis. Widely applied in the preparation of high-potency therapeutic molecules requiring precise 3D orientation and improved pharmacokinetic profiles.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | Ft22,573.02 |
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| 0.250 | 10-20 days | Ft36,326.82 |
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| 1.000 | 10-20 days | Ft96,066.59 |
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| 10.000 | 10-20 days | Ft799,505.02 |
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| 5.000 | 10-20 days | Ft416,603.53 |
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Tert-butyl ((3R,5S)-5-(trifluoromethyl)piperidin-3-yl)carbamate
Used as a key chiral intermediate in the synthesis of biologically active pharmaceuticals, particularly in the development of central nervous system (CNS) agents and protease inhibitors. Its stereochemistry and trifluoromethyl group enhance binding selectivity and metabolic stability in drug candidates. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to its rigid piperidine scaffold and steric protection from the tert-butyl carbamate group, which also serves as a protected amine for stepwise synthesis. Widely applied in the preparation of high-potency therapeutic molecules requiring precise 3D orientation and improved pharmacokinetic profiles.
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| Stable in pH range | - |
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