Tert-butyl trans-3-fluoro-4-hydroxypiperidine-1-carboxylate

97%

  • Product Code: 242618
  CAS:    955029-44-4
Molecular Weight: 219.25 g./mol Molecular Formula: C₁₀H₁₈FNO₃
EC Number: MDL Number: MFCD18791210
Melting Point: Boiling Point:
Density: Storage Condition: 2-8°C, dry, sealed
Product Description: Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of central nervous system (CNS) drugs. Its structural features, including the fluorinated piperidine ring and protected hydroxyl group, make it valuable for constructing bioactive molecules with improved metabolic stability and blood-brain barrier penetration. Commonly employed in the preparation of selective receptor modulators, especially for neurological targets such as serotonin and dopamine receptors. The tert-butyl carbamate (Boc) protection allows for selective functionalization during multi-step syntheses, enabling efficient route design in medicinal chemistry.
Sizes / Availability / Pricing:
Size Availability Price Quantity
0.250 10-20 days ฿2,160.00
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1.000 10-20 days ฿7,240.00
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5.000 10-20 days ฿36,070.00
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10.000 10-20 days ฿72,000.00
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-
0.100 10-20 days ฿1,440.00
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Tert-butyl trans-3-fluoro-4-hydroxypiperidine-1-carboxylate
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of central nervous system (CNS) drugs. Its structural features, including the fluorinated piperidine ring and protected hydroxyl group, make it valuable for constructing bioactive molecules with improved metabolic stability and blood-brain barrier penetration. Commonly employed in the preparation of selective receptor modulators, especially for neurological targets such as serotonin and dopamine receptors. The tert-butyl carbamate (Boc) protection allows for selective functionalization during multi-step syntheses, enabling efficient route design in medicinal chemistry.
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