4-(Trimethylsilyl)benzoic acid

97%

  • Product Code: 242744
  CAS:    15290-29-6
Molecular Weight: 194.30 g./mol Molecular Formula: C₁₀H₁₄O₂Si
EC Number: MDL Number: MFCD00092492
Melting Point: 116.5-117.5 °C Boiling Point: 281.4±23.0 °C(Predicted)
Density: 1.04±0.1 g/cm3(Predicted) Storage Condition: Room temperature, sealed, dry
Product Description: Used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in reactions requiring protection of carboxylic acid groups due to the stability and easy removal of the trimethylsilyl group. Employed in cross-coupling reactions in organic synthesis, where the silyl group enhances reactivity and selectivity. Also applied in the preparation of silyl-protected building blocks for peptide and nucleotide analogs. Its lipophilic character aids in improving solubility in non-aqueous reaction media, facilitating use in chromatography and material science applications.
Sizes / Availability / Pricing:
Size Availability Price Quantity
0.100 10-20 days $110.37
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0.250 10-20 days $185.81
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1.000 10-20 days $486.63
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4-(Trimethylsilyl)benzoic acid
Used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in reactions requiring protection of carboxylic acid groups due to the stability and easy removal of the trimethylsilyl group. Employed in cross-coupling reactions in organic synthesis, where the silyl group enhances reactivity and selectivity. Also applied in the preparation of silyl-protected building blocks for peptide and nucleotide analogs. Its lipophilic character aids in improving solubility in non-aqueous reaction media, facilitating use in chromatography and material science applications.
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