4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)aniline
97%
- Product Code: 243219
CAS:
1259285-61-4
| Molecular Weight: | 287.09 g./mol | Molecular Formula: | C₁₃H₁₇BF₃NO₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD16996236 | |
| Melting Point: | Boiling Point: | 353.7±42.0 °C(Predicted) | |
| Density: | 1.19±0.1 g/cm3(Predicted) | Storage Condition: | 2-8°C, avoiding light |
Product Description:
Widely used in cross-coupling reactions, particularly in Suzuki-Miyaura coupling, this compound serves as a key building block in the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables efficient carbon-carbon bond formation under mild conditions, making it valuable in medicinal chemistry for constructing biaryl systems. The presence of a trifluoromethyl group enhances the lipophilicity and metabolic stability of target molecules, which is advantageous in drug design. It is commonly employed in the development of bioactive compounds, including kinase inhibitors and anti-inflammatory agents. Additionally, it finds use in materials science for creating functional organic materials with tailored electronic properties.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.250 | 10-20 days | $349.38 |
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| 1.000 | 10-20 days | $1,211.09 |
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| 0.100 | 10-20 days | $160.18 |
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4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)aniline
Widely used in cross-coupling reactions, particularly in Suzuki-Miyaura coupling, this compound serves as a key building block in the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables efficient carbon-carbon bond formation under mild conditions, making it valuable in medicinal chemistry for constructing biaryl systems. The presence of a trifluoromethyl group enhances the lipophilicity and metabolic stability of target molecules, which is advantageous in drug design. It is commonly employed in the development of bioactive compounds, including kinase inhibitors and anti-inflammatory agents. Additionally, it finds use in materials science for creating functional organic materials with tailored electronic properties.
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