2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridine

97%

  • Product Code: 243596
  CAS:    881402-16-0
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Density: Storage Condition: -20°C, Inert Gas
Product Description: Widely used in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key boronic ester reagent for constructing carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its pyridine backbone with a trifluoromethyl group enhances electron-withdrawing properties, improving reaction selectivity and stability of intermediates. The boronate ester group allows efficient coupling with aryl or heteroaryl halides under palladium catalysis, making it valuable in the development of complex organic molecules, particularly in drug discovery and materials science. Its stability and reactivity profile support use in automated synthesis and library generation for high-throughput screening.
Sizes / Availability / Pricing:
Size Availability Price Quantity
0.100 10-20 days $136.97
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0.250 10-20 days $222.38
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5.000 10-20 days $2,096.18
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1.000 10-20 days $598.91
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2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridine
Widely used in Suzuki-Miyaura cross-coupling reactions, this compound serves as a key boronic ester reagent for constructing carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its pyridine backbone with a trifluoromethyl group enhances electron-withdrawing properties, improving reaction selectivity and stability of intermediates. The boronate ester group allows efficient coupling with aryl or heteroaryl halides under palladium catalysis, making it valuable in the development of complex organic molecules, particularly in drug discovery and materials science. Its stability and reactivity profile support use in automated synthesis and library generation for high-throughput screening.
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