Tert-Butyl (5-(2-(2,6-Dioxopiperidin-3-Yl)-1-Oxoisoindolin-4-Yl)Pent-4-Yn-1-Yl)Carbamate
98%
- Product Code: 243850
CAS:
2136248-15-0
| Molecular Weight: | 425.48 g./mol | Molecular Formula: | C₂₃H₂₇N₃O₅ |
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| Density: | Storage Condition: | Room temperature |
Product Description:
Used in pharmaceutical research as a key intermediate in the synthesis of targeted protein degradation compounds, particularly PROTACs (Proteolysis Targeting Chimeras). Its alkyne functionality allows for modular assembly via click chemistry, enabling rapid exploration of drug candidates. The structure incorporates a cereblon-binding moiety, facilitating recruitment of E3 ubiquitin ligases to promote degradation of disease-related proteins. Commonly employed in oncology and immunology drug discovery for developing molecules with improved selectivity and prolonged pharmacological activity.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | $1,148.18 |
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Tert-Butyl (5-(2-(2,6-Dioxopiperidin-3-Yl)-1-Oxoisoindolin-4-Yl)Pent-4-Yn-1-Yl)Carbamate
Used in pharmaceutical research as a key intermediate in the synthesis of targeted protein degradation compounds, particularly PROTACs (Proteolysis Targeting Chimeras). Its alkyne functionality allows for modular assembly via click chemistry, enabling rapid exploration of drug candidates. The structure incorporates a cereblon-binding moiety, facilitating recruitment of E3 ubiquitin ligases to promote degradation of disease-related proteins. Commonly employed in oncology and immunology drug discovery for developing molecules with improved selectivity and prolonged pharmacological activity.
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