4-(tetrazol-1-yl)benzoic acid

96%

  • Product Code: 244102
  CAS:    78190-05-3
Molecular Weight: 190.16 g./mol Molecular Formula: C₈H₆N₄O₂
EC Number: MDL Number: MFCD00574246
Melting Point: Boiling Point: 423.3 °C at 760 mmHg
Density: 1.53 g/cm3 Storage Condition: 2-8°C, sealed, dry
Product Description: Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, such as valsartan and other sartan-class antihypertensive drugs. Its tetrazole ring mimics the carboxylic acid group in biological activity, enhancing binding to the AT1 receptor. Also employed in coordination chemistry to form metal-organic frameworks (MOFs) due to its ability to act as a multidentate ligand. Additionally, finds use in medicinal chemistry for developing new bioactive compounds with potential anti-inflammatory or anticancer properties.
Sizes / Availability / Pricing:
Size Availability Price Quantity
0.250 10-20 days $101.18
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1.000 10-20 days $251.52
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5.000 10-20 days $878.44
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4-(tetrazol-1-yl)benzoic acid
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, such as valsartan and other sartan-class antihypertensive drugs. Its tetrazole ring mimics the carboxylic acid group in biological activity, enhancing binding to the AT1 receptor. Also employed in coordination chemistry to form metal-organic frameworks (MOFs) due to its ability to act as a multidentate ligand. Additionally, finds use in medicinal chemistry for developing new bioactive compounds with potential anti-inflammatory or anticancer properties.
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