WT161
10mM in DMSO
- Product Code: 245830
CAS:
1206731-57-8
| Molecular Weight: | 458.55 g./mol | Molecular Formula: | C₂₇H₃₀N₄O₃ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD31563598 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C |
Product Description:
WT161 is used in research settings as a selective inhibitor of the WEE1 kinase, a key protein involved in cell cycle regulation. By inhibiting WEE1, WT161 promotes premature entry of cancer cells into mitosis, especially in cells with p53 deficiencies, leading to increased DNA damage and cell death. This makes it a valuable tool in oncology research, particularly in studies focused on targeted cancer therapies and synthetic lethality approaches. It is often used in combination with DNA-damaging agents such as chemotherapy or radiation to enhance their cytotoxic effects in tumor cells. Due to its mechanism, WT161 is studied for potential applications in treating cancers with specific genetic backgrounds, including certain types of ovarian, lung, and colorectal cancers.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | €172.04 |
+
-
|
WT161
WT161 is used in research settings as a selective inhibitor of the WEE1 kinase, a key protein involved in cell cycle regulation. By inhibiting WEE1, WT161 promotes premature entry of cancer cells into mitosis, especially in cells with p53 deficiencies, leading to increased DNA damage and cell death. This makes it a valuable tool in oncology research, particularly in studies focused on targeted cancer therapies and synthetic lethality approaches. It is often used in combination with DNA-damaging agents such as chemotherapy or radiation to enhance their cytotoxic effects in tumor cells. Due to its mechanism, WT161 is studied for potential applications in treating cancers with specific genetic backgrounds, including certain types of ovarian, lung, and colorectal cancers.
| Mechanism | - |
| Appearance | - |
| Longevity | - |
| Strength | - |
| Storage | - |
| Shelf Life | - |
| Allergen(s) | - |
| Dosage (Range) | - |
| Recommended Dosage | - |
| Dosage (Per Day) | - |
| Recommended Dosage (Per Day) | - |
| Mix Method | - |
| Heat Resistance | - |
| Stable in pH range | - |
| Solubility | - |
| Product Types | - |
| INCI | - |
Purchase History for
Loading purchase history...
Cart
No products
Subtotal:
€0.00
€0.00
Total :