Wilfornine A
98%
- Product Code: 245904
CAS:
345954-00-9
| Molecular Weight: | 925.89 g./mol | Molecular Formula: | C₄₅H₅₁NO₂₀ |
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| Melting Point: | Boiling Point: | 890.4±65.0 °C(Predicted) | |
| Density: | 1.42±0.1 g/cm3(Predicted) | Storage Condition: | 2-8°C, sealed, dry |
Product Description:
Wilfornine A exhibits significant antifungal activity, particularly against pathogenic Candida species, making it a promising candidate for development as an antifungal therapeutic agent. It has demonstrated the ability to disrupt fungal cell membrane integrity by interacting with ergosterol biosynthesis pathways, a mechanism similar to azole-class antifungals but with potentially lower susceptibility to common resistance mechanisms. Due to its natural origin and selective toxicity, Wilfornine A is being investigated for use in treating systemic fungal infections, especially those involving drug-resistant strains. Additionally, its structural framework is being explored in medicinal chemistry for the design of novel derivatives with enhanced bioavailability and spectrum of activity. Research is ongoing to evaluate its efficacy in topical formulations and its potential application in agricultural antifungals to combat crop-threatening fungi without harming mammalian cells.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 | 10-20 days | $1,800.48 |
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Wilfornine A
Wilfornine A exhibits significant antifungal activity, particularly against pathogenic Candida species, making it a promising candidate for development as an antifungal therapeutic agent. It has demonstrated the ability to disrupt fungal cell membrane integrity by interacting with ergosterol biosynthesis pathways, a mechanism similar to azole-class antifungals but with potentially lower susceptibility to common resistance mechanisms. Due to its natural origin and selective toxicity, Wilfornine A is being investigated for use in treating systemic fungal infections, especially those involving drug-resistant strains. Additionally, its structural framework is being explored in medicinal chemistry for the design of novel derivatives with enhanced bioavailability and spectrum of activity. Research is ongoing to evaluate its efficacy in topical formulations and its potential application in agricultural antifungals to combat crop-threatening fungi without harming mammalian cells.
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