((Z)-2-((3S,5R)-3,5-Bis((Tert-Butyldimethylsilyl)Oxy)-2-Methylenecyclohexylidene)Ethyl)Diphenylphosphine Oxide

98%

  • Product Code: 246810
  CAS:    81522-68-1
Molecular Weight: 582.9 g./mol Molecular Formula: C₃₃H₅₁O₃PSi₂
EC Number: MDL Number:
Melting Point: Boiling Point:
Density: Storage Condition: Room temperature
Product Description: Used as a key intermediate in organic synthesis, particularly in the preparation of complex natural products and pharmaceuticals. Its phosphine oxide functionality enables Horner-Wadsworth-Emmons olefination reactions, allowing stereoselective formation of α,β-unsaturated systems with high (Z)-selectivity. The silyl-protected hydroxyl groups provide stability and compatibility with multi-step synthetic sequences, while allowing selective deprotection for further functionalization. Commonly employed in the synthesis of bioactive molecules such as vitamin D analogs and terpenoids where precise stereochemical control is required.
Sizes / Availability / Pricing:
Size Availability Price Quantity
0.100 10-20 days $463.13
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0.250 10-20 days $771.46
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1.000 10-20 days $1,894.20
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((Z)-2-((3S,5R)-3,5-Bis((Tert-Butyldimethylsilyl)Oxy)-2-Methylenecyclohexylidene)Ethyl)Diphenylphosphine Oxide
Used as a key intermediate in organic synthesis, particularly in the preparation of complex natural products and pharmaceuticals. Its phosphine oxide functionality enables Horner-Wadsworth-Emmons olefination reactions, allowing stereoselective formation of α,β-unsaturated systems with high (Z)-selectivity. The silyl-protected hydroxyl groups provide stability and compatibility with multi-step synthetic sequences, while allowing selective deprotection for further functionalization. Commonly employed in the synthesis of bioactive molecules such as vitamin D analogs and terpenoids where precise stereochemical control is required.
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