N-Ethylmaleimide
Ultra pure grade, 99.0%
- Product Code: 56425
Alias:
N-Ethylmaleimide ; N-Ethylmaleimide, N-Ethylmaleimide, N-Ethylmaleimide
CAS:
128-53-0
| Molecular Weight: | 125.13 g./mol | Molecular Formula: | C₆H₇NO₂ |
|---|---|---|---|
| EC Number: | 204-892-4 | MDL Number: | MFCD00005509 |
| Melting Point: | 43-46 °C(lit.) | Boiling Point: | 210 °C(lit.) |
| Density: | Storage Condition: | 2~8°C |
Product Description:
N-Ethylmaleimide is widely used in biochemical research as a selective reagent to modify cysteine residues in proteins. It effectively blocks thiol groups, making it valuable for studying enzyme mechanisms and protein functions by inhibiting cysteine-dependent enzymes. This property is particularly useful in understanding protein structure and interactions. Additionally, it is employed in the study of membrane transport processes, where it inhibits certain ATPases by reacting with their cysteine residues. In cell biology, N-Ethylmaleimide is used to investigate vesicular trafficking and fusion events, as it disrupts SNARE protein function. Its ability to alkylate thiols also makes it a tool for probing redox-sensitive processes in cells.
Product Specification:
| Test | Specification |
|---|---|
| Al | 0-5 ppm |
| BA | 0-5 |
| BI | 0-5 |
| CA | 0-10 |
| CD | 0-5 |
| CO | 0-5 ppm |
| CR | 0-5 ppm |
| Cu | 0-5 ppm |
| Fe | 0-5 ppm |
| K | 0-500 ppm |
| LI | 0-5 ppm |
| Melting point | 44-47 |
| MG | 0-5 |
| MN | 0-5 |
| MO | 0-5 ppm |
| NA | 0-50 |
| NI | 0-500 |
| PB | 0-20 |
| Purity (HPLC) | 99-100% |
| SR | 0-5 ppm |
| Zn | 0-5 ppm |
| Absorption | 1M 382 nm, Methanol cut-off |
| Appearance | White to off-white powder, crystals and/or chunks |
| Infrared Spectrum | Conforms to Structure |
| Solubility (Methanol) | Soluble 1 m at 20 |
| Note | Low melting point solid; may change state in different environments (solid, liquid, or semi-solid) |
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1.000 G | 10-20 days | ฿1,110.00 |
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| 5.000 G | 10-20 days | ฿2,530.00 |
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| 25.000 G | 10-20 days | ฿8,480.00 |
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| 100.000 G | 10-20 days | ฿24,890.00 |
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N-Ethylmaleimide
N-Ethylmaleimide is widely used in biochemical research as a selective reagent to modify cysteine residues in proteins. It effectively blocks thiol groups, making it valuable for studying enzyme mechanisms and protein functions by inhibiting cysteine-dependent enzymes. This property is particularly useful in understanding protein structure and interactions. Additionally, it is employed in the study of membrane transport processes, where it inhibits certain ATPases by reacting with their cysteine residues. In cell biology, N-Ethylmaleimide is used to investigate vesicular trafficking and fusion events, as it disrupts SNARE protein function. Its ability to alkylate thiols also makes it a tool for probing redox-sensitive processes in cells.
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| Mix Method | - |
| Heat Resistance | - |
| Stable in pH range | - |
| Solubility | - |
| Product Types | - |
| INCI | - |
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