Boc-N-alpha-Methyl-O-benzyl-L-tyrosine
98%
- Product Code: 104829
Alias:
Boc-N-methyl-O-benzyl-L-tyrosine ; N-tert-butoxycarbonyl-N-methyl-O-benzyl-L-tyrosine
CAS:
64263-81-6
Molecular Weight: | 385.45 g./mol | Molecular Formula: | C₂₂H₂₇NO₅ |
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EC Number: | MDL Number: | MFCD00038755 | |
Melting Point: | Boiling Point: | ||
Density: | Storage Condition: | 2~8°C |
Product Description:
This compound is primarily used in peptide synthesis as a protected amino acid derivative. Its Boc (tert-butoxycarbonyl) group serves as a temporary protecting group for the amine functionality, while the benzyl group protects the hydroxyl group of tyrosine. This protection strategy allows for selective reactions during peptide chain assembly, particularly in solid-phase peptide synthesis (SPPS). It is valuable in the production of complex peptides and proteins, where precise control over amino acid coupling is essential. Additionally, it finds applications in the development of peptide-based pharmaceuticals, where modifications like N-alpha-methylation can enhance stability, bioavailability, or receptor binding affinity. Its use is also relevant in research settings for studying peptide structure-activity relationships and designing novel bioactive molecules.
Product Specification:
Test | Specification |
---|---|
Melting Point | 0 |
Purity (HPLC) | 98-100 |
Specific Rotation [A]20/D(C=1, Ethanol) | 0 |
300 MHz NMR Spectrum 1H | Conforms to Structure |
Appearance | Beige Powder |
Sizes / Availability / Pricing:
Size (g) | Availability | Price | Quantity |
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0.250 | 10-20 days | ฿1,026.00 |
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1.000 | 10-20 days | ฿2,565.00 |
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5.000 | 10-20 days | ฿8,397.00 |
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25.000 | 10-20 days | ฿34,497.00 |
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Boc-N-alpha-Methyl-O-benzyl-L-tyrosine
This compound is primarily used in peptide synthesis as a protected amino acid derivative. Its Boc (tert-butoxycarbonyl) group serves as a temporary protecting group for the amine functionality, while the benzyl group protects the hydroxyl group of tyrosine. This protection strategy allows for selective reactions during peptide chain assembly, particularly in solid-phase peptide synthesis (SPPS). It is valuable in the production of complex peptides and proteins, where precise control over amino acid coupling is essential. Additionally, it finds applications in the development of peptide-based pharmaceuticals, where modifications like N-alpha-methylation can enhance stability, bioavailability, or receptor binding affinity. Its use is also relevant in research settings for studying peptide structure-activity relationships and designing novel bioactive molecules.
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