Glycyrrhetinic acid (Enoxolone)

Glycyrrhetinic acid (Enoxolone)


Glycyrrhetinic Acid (enoxolone), extracted from Licorice or the licorice tree, has an anti-irritant effect. (anti-irritation) and reduce inflammation (anti-inflammation) of the skin Maiden Maiden

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Expiration: 06/2025 (Lot: 9QBQ05)

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  • Technical
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Glycyrrhetinic Acid (type 18b), commonly known as enoxolone, extracted from Licorice or the licorice tree, has an anti-irritant effect. (anti-irritation) and reduce inflammation (anti-inflammation) of the skin Maiden


In-vitro results:


From the experiment to measure Peroxidase activity, which indicates the level of inflammation of the skin, it was found that when used Phyto Glycyrrhetinic Acid can help reduce Maiden Peroxidase activity was 75% compared to the untreated control group. Maiden


Use: Can be used in all skin care products

Mixing method: Mix in Glycol to dissolve By using heat 60-70 degrees to help melt and then add the solder to the formula.

Usage rate: 0.1-3% (recommended 1%)

Product characteristics: white/light powder

Solubility: can dissolve in Ethanol , Propylene glycol , Ethoxydiglycol , Butylene Glycol , Glycerin By using heat 60-70 degrees to help melt Maiden

Storage:   For long term storage Store in the refrigerator, away from light and heat, seal the lid tightly, at least 4 years shelf life *Light will cause Glycyrrhetinic Acid to deteriorate faster. Please avoid light*


INCI Name : Glycyrrhetinic Acid (Type 18b)


Examples of products used Glycyrrhetinic Acid as an element in the formula

Atopiclair - Atopic Dermatitis Cream


Bioderma Sensibio AR Cream - Prevents and relieves redness/inflammation of the skin.


LA MER Illuminating eye gel


Clarins Skin Beauty Repair SOS treatment


Estee Lauder Re-Nutriv Ultimate Lift Rejuvenating Soft Creme


Storage: Store under room temperature. Avoid Heat & Light.

Shelf Life: 48Months from manufacturing or testing date (Current Lot will expire: 06/2025)

Dosage (Range): 0.1% - 3%

Recommended Dosage: 1%

Mix Method: Please follow instruction under product info carefully.

Heat Resistance: Avoid heat above 70C

Stable in pH range: 4 - 6.5

Solubility: Most glycols , Ethoxydiglycol , Ethanol, organic solvents

Product Types: Cream , Lotion , Mask

INCI: Glycyrrhetinic acid

Product Specification:

Test Specification
Appearance White or almost white crystalline powder
IR Absorption Complies
Thin Layer Chromatography Complies
Color reaction Pink colour
Appearance of solution Clear and not more intensely coloured than reference solution
Heavy metals 20ppm Max
Loss on drying 0.5% Max
Sulphated Ash 0.2% Max
Related substances (Total) 2.0% Max
Related substances (Impurities) 0.7% Max
Specific optical rotation +145 - +154 (dried subtances)
Residual ethanol 0.5% Max
Assay (potentiometry) 98.0-101.0%


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