pure melatonin   Has a powerful anti-oxidant effect Helps to prolong the life of the outer skin cells , regulates the action of collagenases , Can help inhibit redness of the skin (etythema) when damaged by UV light. , stimulate hair regrowth Reduce hair loss

Pure-Melatonine™ - Pure Melatonin

Melatonin has a powerful anti-oxidant effect compared to other antioxidants, and it has the advantage of being absorbed into the skin well. With a lipophillic nature (good with oil) when on various skin layers. So it can be absorbed well. Nowadays, it is commonly used as an anti-aging ingredient for skin.

In addition, there are research findings during 10 years ago For the various benefits of Melatonin on the skin, the benefits are found as follows:

Proliferation of keratinocytes (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914270/ , https://iv.iiarjournals.org/content/23/5/739.full)or helping to extend the life of the outer skin cells Makes the skin have a better defense island (improve skin barrier).

Melatonin downregulates collagenases including MMP-1, MMP-3 and MMP-10 (https://www.researchgate.net/publication/45100000)Regulates the activity of collagenases, which are enzymes. that acts to decompose collagen make collagen under the skin longer life

Melatonin suppresses erythema when applied before UV exposure (https://www.researchgate.net/publication/232451181)Can help stop redness of the skin (etythema) when damaged by UV light.

Topical Melatonin for Treatment of Androgenetic Alopecia Melatonin stimulates hair growth. Reduce hair loss

Based on experimental results (ref: Int J Trichology. 2012 OctDec; Table 1). 4(4): 236–245. Research Name: Topical Melatonin for Treatment of Androgenetic Alopecia. Tobias W Fischer, Ralph M Trüeb, Gabriella Hänggi, Marcello Innocenti, and Peter Elsner. ) It was found that the use of 0.1% melatonin helped reduce hair loss. and stimulates hair regrowth by 48.2% of all users After 90 days of continuous use and results have continued to improve. After 180 days of continuous use with users 32.1% of all users.

(Please see the research results in the brochure attachment)

IMPORTANT: Melatonin is air sensitive when exposed to air continuously. will deteriorate Finished products that use melatonin as an ingredient must be protected from air, for example finished product packaging. In a vacuum tube (vacuum tube). Do not pack the product in a jar. that the formula can be continuously exposed to the air (Continued exposure to air causes a deterioration of Melatonin by more than 60% after 15 days of continuous exposure to air.)

Use: For any form of skin care products, for hair care/hair regrowth products.

Mixing method: mix into the recipe in the last step Avoid prolonged exposure to air, and the pH of the formula must be in the range of 4-10 and do not expose to heat.

Usage rate: 0.1-3%

Product characteristics: white powder

Solubility: Soluble in some oils and some glycol (eg ethoxydiglycol), 1,3-Propanediol

Storage: Store in the refrigerator, temperature 5-10 degrees, do not expose to sunlight, heat, air, seal the lid tightly, shelf life at least 2 years.

INCI Name : Melatonin

Examples of products that use melatonin as the main ingredient of the formula