Ceramide 3 (Ceramide NP, N-stearoyl-phytosphingosine)
- Product Code: 239133
Ceramide 3 (Ceramide 3, now known as Ceramide NP) Powder type, purity more than 90% It has a structure similar to Ceramide under the human skin.
Type: N-stearoyl-phytosphingosine (Same as : Croda Y3S, Evonik Ceramide III)
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| Test Name | Specification |
|---|---|
| Appearance | White to off-white powder |
| Melting point | 98-108°C |
| Identification | HPLC Conforms |
| Loss of drying | NMT 2.0% |
| Heavy metals | NMT 20ppm |
| Residue on ignition | NMT 0.5% |
| Total aerobic bacteria | NMT 500CFU/g |
| Yeast &Mold | NMT 100CFU/g |
| Methanol | NMT3000ppm |
| Ethyl oleate | NMT2000ppm |
| Purity (HPLC-UV) | A:NLT 85.0% A+B+C+D: NLT 95% |
| Assay(HPLC-UV) | A:NLT 85.0% NLT 95.0% (A+B+C+D) |
Ceramide 3 (Ceramide 3, now known as Ceramide NP) Powder type, purity more than 90% It has a structure similar to Ceramide under the human skin.
Type: N-stearoyl-phytosphingosine (Same as : Croda Y3S, Evonik Ceramide III)
| Type of Ceramide NP | Fatty-acyl chain (top zig-zag) | Physical form at 25 °C | Melting (°C) | Packing in model SC bilayers | Remarks |
|---|---|---|---|---|---|
| N-oleoyl-phytosphingosine | C 18:1 Δ9 cis (oleic) – one double bond | viscous, semi-solid | ≈ 38–45 °C | predominantly hexagonal / fluid | • Much more fluid than NP → easier to disperse. • Improves sensorial feel; good for compromised or very dry skin because it lowers lamellar rigidity. • One double bond = moderate oxidation risk (needs tocopherol). |
| N-linoleoyl-phytosphingosine | C 18:2 Δ9,12 cis (linoleic) – two double bonds | viscous oil | ≈ 25–30 °C | highly fluid, liquid-crystalline | • Very fluid – acts almost like an internal “skin lipid plasticiser”. • Linoleic acid is an essential FA for in vivo synthesis of true acyl-ceramide (Cer EOS); topical LP can serve as a biochemical precursor. • Highest oxidation liability → antioxidant system is mandatory; short shelf-life if unprotected. |
| N-stearoyl-phytosphingosine | C 18:0 (stearic) – fully saturated | waxy solid / powder | ≈ 80–90 °C | highly ordered orthorhombic | • Most abundant epidermal ceramide after EOS. • Builds a very tight, impermeable barrier, but is hard to dissolve—usually pre-dispersed or made in-situ from alkaline-earth salts. • Excellent oxidative stability; longest shelf-life. |
Use: The main ingredient in moisturizer products for sensitive skin, dry skin, aging skin, aging skin.
How to mix: Mix in the oil portion of the formula. Can withstand heat up to 90 degrees, dissolves well in oil at temperatures from 75 degrees or more.
Utilization rate: 0.01-0.2% (0.1% recommended)
Product characteristics: White-light yellow powder
Solubility: It can dissolve in oil and some fatty alcohols.
Storage: Valid for 24 months, please store in the refrigerator at 6 °C -8 °C Mixed cosmetics should be stored in the refrigerator.
INCI Name : Ceramide 3 (new INCI "Ceramide NP")
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Ceramide 3 (Ceramide NP, N-stearoyl-phytosphingosine)
Ceramide 3 (Ceramide 3, now known as Ceramide NP) Powder type, purity more than 90% It has a structure similar to Ceramide under the human skin.
Type: N-stearoyl-phytosphingosine (Same as : Croda Y3S, Evonik Ceramide III)
Ceramide 3 (Ceramide 3, now known as Ceramide NP) Powder type, purity more than 90% It has a structure similar to Ceramide under the human skin.
Type: N-stearoyl-phytosphingosine (Same as : Croda Y3S, Evonik Ceramide III)
| Type of Ceramide NP | Fatty-acyl chain (top zig-zag) | Physical form at 25 °C | Melting (°C) | Packing in model SC bilayers | Remarks |
|---|---|---|---|---|---|
| N-oleoyl-phytosphingosine | C 18:1 Δ9 cis (oleic) – one double bond | viscous, semi-solid | ≈ 38–45 °C | predominantly hexagonal / fluid | • Much more fluid than NP → easier to disperse. • Improves sensorial feel; good for compromised or very dry skin because it lowers lamellar rigidity. • One double bond = moderate oxidation risk (needs tocopherol). |
| N-linoleoyl-phytosphingosine | C 18:2 Δ9,12 cis (linoleic) – two double bonds | viscous oil | ≈ 25–30 °C | highly fluid, liquid-crystalline | • Very fluid – acts almost like an internal “skin lipid plasticiser”. • Linoleic acid is an essential FA for in vivo synthesis of true acyl-ceramide (Cer EOS); topical LP can serve as a biochemical precursor. • Highest oxidation liability → antioxidant system is mandatory; short shelf-life if unprotected. |
| N-stearoyl-phytosphingosine | C 18:0 (stearic) – fully saturated | waxy solid / powder | ≈ 80–90 °C | highly ordered orthorhombic | • Most abundant epidermal ceramide after EOS. • Builds a very tight, impermeable barrier, but is hard to dissolve—usually pre-dispersed or made in-situ from alkaline-earth salts. • Excellent oxidative stability; longest shelf-life. |
Use: The main ingredient in moisturizer products for sensitive skin, dry skin, aging skin, aging skin.
How to mix: Mix in the oil portion of the formula. Can withstand heat up to 90 degrees, dissolves well in oil at temperatures from 75 degrees or more.
Utilization rate: 0.01-0.2% (0.1% recommended)
Product characteristics: White-light yellow powder
Solubility: It can dissolve in oil and some fatty alcohols.
Storage: Valid for 24 months, please store in the refrigerator at 6 °C -8 °C Mixed cosmetics should be stored in the refrigerator.
INCI Name : Ceramide 3 (new INCI "Ceramide NP")
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