7-Aminoactinomycin D (7-AAD)

98%

  • Product Code: 107392
  CAS:    7240-37-1
Molecular Weight: 1270.43 g./mol Molecular Formula: C₆₂H₈₇N₁₃O₁₆
EC Number: MDL Number:
Melting Point: Boiling Point:
Density: Storage Condition: -20°C, airtight, dry
Product Description: 7-Aminoactinomycin D (7-AAD) is widely used in biological research for its ability to bind to DNA, making it a valuable tool in cell biology and immunology. It is commonly employed in flow cytometry to distinguish between viable and non-viable cells. By selectively staining dead or dying cells with compromised membranes, 7-AAD helps researchers assess cell viability and apoptosis in various experimental setups. Additionally, it is used in combination with other fluorescent markers to study cell cycle dynamics, as it can intercalate into double-stranded DNA and provide insights into cellular DNA content. This makes it particularly useful in cancer research, where understanding cell proliferation and death is critical. Its application extends to immunophenotyping, where it aids in identifying specific cell populations in complex mixtures, such as blood or tissue samples. Overall, 7-AAD is a versatile reagent in life sciences, contributing to advancements in cellular analysis and disease research.
Product Specification:
Test Specification
Appearance Red To Dark Purple Powder
Purity (%) 97.5-100
Infrared Spectrum Conforms To Structure
NMR Conforms To Structure
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.001 10-20 days ฿11,070.00
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7-Aminoactinomycin D (7-AAD)
7-Aminoactinomycin D (7-AAD) is widely used in biological research for its ability to bind to DNA, making it a valuable tool in cell biology and immunology. It is commonly employed in flow cytometry to distinguish between viable and non-viable cells. By selectively staining dead or dying cells with compromised membranes, 7-AAD helps researchers assess cell viability and apoptosis in various experimental setups. Additionally, it is used in combination with other fluorescent markers to study cell cycle dynamics, as it can intercalate into double-stranded DNA and provide insights into cellular DNA content. This makes it particularly useful in cancer research, where understanding cell proliferation and death is critical. Its application extends to immunophenotyping, where it aids in identifying specific cell populations in complex mixtures, such as blood or tissue samples. Overall, 7-AAD is a versatile reagent in life sciences, contributing to advancements in cellular analysis and disease research.
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