Flavonoid glycosides derived from quercetin have gained attention for their topical benefits, particularly due to their antioxidant, anti-inflammatory, and skin-protective properties.

Isoquercitrin, a flavonoid glycoside derived from quercetin, has gained attention for its skin benefits, particularly due to its antioxidant, anti-inflammatory, and skin-protective properties.

Used in many Eucerin products.

Below is a summary of the skin benefits of isoquercitrin, supported by research references:

1. Antioxidant activity
Isoquercitrin has powerful antioxidant properties, helping to counteract free radicals and reduce oxidative stress in the skin, helping to prevent premature aging and damage caused by environmental factors such as UV rays.

Research: Kim, YJ and Kim, YA (2013). Antioxidant and antiproliferative activity of isoquercitrin from Acer mono leaves. Journal of Medicinal Plants Research, 7(17), 1234-1240.

2. Anti-inflammatory properties
It has been found to inhibit inflammation, reduce redness, swelling and irritation on the skin, making it useful for conditions such as eczema, psoriasis and acne.

Research: Lee, SJ et al. (2010) Anti-inflammatory effects of isoquercitrin on LPS-induced inflammation in RAW 264.7 macrophages. Journal of Ethnopharmacology, 129(2), 207-214.

3. UV protection
Isoquercitrin can protect skin from UV-induced damage by scavenging reactive oxygen radicals (ROS) and reducing inflammation induced by UV exposure.

Research: Vicentini, FT et al. (2011) Quercetin and isoquercitrin attenuate UVB-induced oxidative stress and inflammation in human skin fibroblasts. Journal of Photochemistry and Photobiology B: Biology, 104(1-2), 132-137.

4. Wound treatment
Promote wound healing by enhancing collagen synthesis and reducing oxidative stress at the wound site.

Research: Park, JH, et al. (2015). Isoquercitrin accelerates wound healing by promoting angiogenesis and collagen synthesis. Biochemical and Biophysical Research Communications, 463(4), 781-786.

5. Improving the skin's protective barrier
Isoquercitrin helps strengthen the skin barrier by improving moisture retention and reducing transepidermal water loss (TEWL), making it beneficial for dry or sensitive skin.

Research: Kim, HJ et al. (2016) Effects of isoquercitrin on skin barrier function and moisture in atopic dermatitis mice. Dermatology Journal 83(2), 136-143.

6. Anti-aging
By reducing oxidative stress and promoting collagen production, isoquercitrin can help reduce the appearance of fine lines and sagging skin.

Research: Hwang, E. et al. (2017). Isoquercitrin improves skin elasticity by regulating collagen synthesis and degradation in UVB-irradiated hairless mice. Journal of Cosmetic Dermatology, 16(4), 521-528.

7. Antimicrobial properties
It has been shown to have antimicrobial and antifungal properties, making it useful in treating acne or other skin infections.

Research: Cushnie, TP and Lamb, AJ (2005) Antimicrobial activity of flavonoids. International Journal of Antimicrobial Agents, 26(5), 343-356.

Usage: It can be used in any cosmetic product because of its many benefits.

Mixing method: Mix the formula ingredients into the water.

Usage rate: 0.1-1.0%

Product Description: Creamy white to beige powder.

Solubility: Soluble in glycols, ethanol

Storage method: For long-term storage, keep in the refrigerator, avoid exposure to light or heat, close the lid tightly, shelf life of at least 2 years.

INCI Name : Isoquercitrin