E-4031
≥98%
- Product Code: 100411
CAS:
113559-13-0
| Molecular Weight: | 474.44 g./mol | Molecular Formula: | C₂₁H₂₉Cl₂N₃O₃S |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8℃ |
Product Description:
E-4031 is primarily utilized in research settings to study cardiac electrophysiology due to its specific action as a potent blocker of the hERG potassium channel. This channel plays a critical role in the repolarization phase of the cardiac action potential, and E-4031 is often used to investigate arrhythmias and the mechanisms underlying long QT syndrome. By inhibiting hERG, it helps researchers understand the impact of delayed repolarization on heart function and assess the potential cardiotoxicity of new drugs. Additionally, it serves as a tool in preclinical studies to evaluate the safety profiles of pharmaceutical compounds, particularly those that may inadvertently interfere with hERG channels.
Product Specification:
| Test | Specification |
|---|---|
| Appearance | White To Off-White Solid |
| Purity (%) | 98 |
| 1 H Nmr Spectrum | Consistent With Structure |
| Infrared Spectrum | Conforms To Structure |
| Lcms | Consistent With Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 | 10-20 days | ฿4,590.00 |
+
-
|
| 0.010 | 10-20 days | ฿7,900.00 |
+
-
|
| 0.050 | 10-20 days | ฿32,910.00 |
+
-
|
E-4031
E-4031 is primarily utilized in research settings to study cardiac electrophysiology due to its specific action as a potent blocker of the hERG potassium channel. This channel plays a critical role in the repolarization phase of the cardiac action potential, and E-4031 is often used to investigate arrhythmias and the mechanisms underlying long QT syndrome. By inhibiting hERG, it helps researchers understand the impact of delayed repolarization on heart function and assess the potential cardiotoxicity of new drugs. Additionally, it serves as a tool in preclinical studies to evaluate the safety profiles of pharmaceutical compounds, particularly those that may inadvertently interfere with hERG channels.
| Mechanism | - |
| Appearance | - |
| Longevity | - |
| Strength | - |
| Storage | - |
| Shelf Life | - |
| Allergen(s) | - |
| Dosage (Range) | - |
| Recommended Dosage | - |
| Dosage (Per Day) | - |
| Recommended Dosage (Per Day) | - |
| Mix Method | - |
| Heat Resistance | - |
| Stable in pH range | - |
| Solubility | - |
| Product Types | - |
| INCI | - |
Cart
No products
Subtotal:
฿0.00
฿0.00
Total :