EPZ004777
99%
- Product Code: 100442
CAS:
1338466-77-5
| Molecular Weight: | 539.67 g./mol | Molecular Formula: | C₂₈H₄₁N₇O₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD25563264 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20℃ |
Product Description:
EPZ004777 is primarily used in research settings to study the role of histone methyltransferases in gene regulation. It is a selective inhibitor of DOT1L, an enzyme involved in the methylation of histone H3, which plays a critical role in chromatin structure and gene expression. By inhibiting DOT1L, this compound helps researchers investigate its impact on cellular processes, particularly in the context of cancer biology. It has been utilized in studies focusing on leukemia, where aberrant DOT1L activity is linked to disease progression. Additionally, EPZ004777 serves as a tool to explore potential therapeutic strategies targeting epigenetic modifications in various diseases.
Product Specification:
| Test | Specification |
|---|---|
| Appearance | White To Off-White Powder |
| Purity (%) | 98.5-100 |
| Infrared Spectrum | Conforms To Structure |
| NMR | Conforms To Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 | 10-20 days | ฿24,680.00 |
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EPZ004777
EPZ004777 is primarily used in research settings to study the role of histone methyltransferases in gene regulation. It is a selective inhibitor of DOT1L, an enzyme involved in the methylation of histone H3, which plays a critical role in chromatin structure and gene expression. By inhibiting DOT1L, this compound helps researchers investigate its impact on cellular processes, particularly in the context of cancer biology. It has been utilized in studies focusing on leukemia, where aberrant DOT1L activity is linked to disease progression. Additionally, EPZ004777 serves as a tool to explore potential therapeutic strategies targeting epigenetic modifications in various diseases.
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