Etomoxir (Na salt)

99%

  • Product Code: 100485
  CAS:    828934-41-4
Molecular Weight: 320.74 g./mol Molecular Formula: C₁₅H₁₈ClO₄Na
EC Number: MDL Number: MFCD07787411
Melting Point: Boiling Point:
Density: Storage Condition: -20℃
Product Description: Etomoxir (Na salt) is primarily used in research to study metabolic pathways, particularly those involving fatty acid oxidation. It acts as a potent inhibitor of carnitine palmitoyltransferase-1 (CPT-1), an enzyme crucial for the transport of long-chain fatty acids into mitochondria for oxidation. By inhibiting CPT-1, etomoxir shifts cellular energy metabolism from fatty acid oxidation to glucose utilization. This property makes it a valuable tool in investigating metabolic disorders, such as diabetes, obesity, and heart disease, where altered fatty acid metabolism plays a significant role. Additionally, etomoxir has been explored in cancer research to understand the metabolic reprogramming of cancer cells, which often rely on altered energy pathways for survival and growth. Its application extends to studying the impact of metabolic changes on cellular function and disease progression.
Product Specification:
Test Specification
Appearance White To Pale-Yellow Powder Or Crystals
Purity (%) 98.5-100
Infrared Spectrum Conforms To Structure
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.005 10-20 days ฿4,160.00
+
-
0.025 10-20 days ฿10,680.00
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Etomoxir (Na salt)
Etomoxir (Na salt) is primarily used in research to study metabolic pathways, particularly those involving fatty acid oxidation. It acts as a potent inhibitor of carnitine palmitoyltransferase-1 (CPT-1), an enzyme crucial for the transport of long-chain fatty acids into mitochondria for oxidation. By inhibiting CPT-1, etomoxir shifts cellular energy metabolism from fatty acid oxidation to glucose utilization. This property makes it a valuable tool in investigating metabolic disorders, such as diabetes, obesity, and heart disease, where altered fatty acid metabolism plays a significant role. Additionally, etomoxir has been explored in cancer research to understand the metabolic reprogramming of cancer cells, which often rely on altered energy pathways for survival and growth. Its application extends to studying the impact of metabolic changes on cellular function and disease progression.
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