GNE-617
≥99%
- Product Code: 100695
CAS:
1362154-70-8
| Molecular Weight: | 427.42 g./mol | Molecular Formula: | C₂₁H₁₅F₂N₃O₃S |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8℃ |
Product Description:
GNE-617 is primarily utilized in the field of cancer research, particularly in the study of metabolic pathways in tumor cells. It functions as a potent and selective inhibitor of nicotinamide phosphoribosyltransferase (NAMPT), an enzyme crucial for the biosynthesis of nicotinamide adenine dinucleotide (NAD+). By inhibiting NAMPT, GNE-617 disrupts NAD+ production, leading to energy depletion and ultimately inducing cell death in cancer cells. This makes it a valuable tool for investigating the role of NAD+ metabolism in cancer progression and for exploring potential therapeutic strategies targeting metabolic vulnerabilities in tumors. Additionally, GNE-617 is used in preclinical studies to evaluate the efficacy of NAMPT inhibition in various cancer models, helping to identify potential biomarkers and optimize treatment regimens.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.002 | 10-20 days | ฿11,961.00 |
+
-
|
| 0.005 | 10-20 days | ฿17,784.00 |
+
-
|
GNE-617
GNE-617 is primarily utilized in the field of cancer research, particularly in the study of metabolic pathways in tumor cells. It functions as a potent and selective inhibitor of nicotinamide phosphoribosyltransferase (NAMPT), an enzyme crucial for the biosynthesis of nicotinamide adenine dinucleotide (NAD+). By inhibiting NAMPT, GNE-617 disrupts NAD+ production, leading to energy depletion and ultimately inducing cell death in cancer cells. This makes it a valuable tool for investigating the role of NAD+ metabolism in cancer progression and for exploring potential therapeutic strategies targeting metabolic vulnerabilities in tumors. Additionally, GNE-617 is used in preclinical studies to evaluate the efficacy of NAMPT inhibition in various cancer models, helping to identify potential biomarkers and optimize treatment regimens.
| Mechanism | - |
| Appearance | - |
| Longevity | - |
| Strength | - |
| Storage | - |
| Shelf Life | - |
| Allergen(s) | - |
| Dosage (Range) | - |
| Recommended Dosage | - |
| Dosage (Per Day) | - |
| Recommended Dosage (Per Day) | - |
| Mix Method | - |
| Heat Resistance | - |
| Stable in pH range | - |
| Solubility | - |
| Product Types | - |
| INCI | - |
Cart
No products
Subtotal:
฿0.00
฿0.00
Total :