GNF-5
>98%
- Product Code: 100703
CAS:
778277-15-9
| Molecular Weight: | 418.37 g./mol | Molecular Formula: | C₂₀H₁₇F₃N₄O₃ |
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| Density: | Storage Condition: | -20℃ |
Product Description:
GNF-5 is primarily utilized in research settings as a potent and selective inhibitor of the Bcr-Abl tyrosine kinase, particularly targeting the T315I mutant form. Its application is significant in the study of chronic myeloid leukemia (CML) and other cancers driven by Bcr-Abl mutations. Researchers employ GNF-5 to investigate resistance mechanisms in cancer therapies, especially in cases where patients develop resistance to first-line treatments like imatinib. Additionally, it serves as a valuable tool in preclinical studies to evaluate the efficacy of novel therapeutic strategies aimed at overcoming drug resistance in cancer treatment.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.050 | 10-20 days | ฿5,454.00 |
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GNF-5
GNF-5 is primarily utilized in research settings as a potent and selective inhibitor of the Bcr-Abl tyrosine kinase, particularly targeting the T315I mutant form. Its application is significant in the study of chronic myeloid leukemia (CML) and other cancers driven by Bcr-Abl mutations. Researchers employ GNF-5 to investigate resistance mechanisms in cancer therapies, especially in cases where patients develop resistance to first-line treatments like imatinib. Additionally, it serves as a valuable tool in preclinical studies to evaluate the efficacy of novel therapeutic strategies aimed at overcoming drug resistance in cancer treatment.
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