NVP-HSP990
≥98%
- Product Code: 100867
CAS:
934343-74-5
| Molecular Weight: | 379.39 g./mol | Molecular Formula: | C₂₀H₁₈FN₅O₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD22628859 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20℃ |
Product Description:
NVP-HSP990 is primarily utilized in the field of cancer research as a potent and selective inhibitor of heat shock protein 90 (HSP90). This protein plays a crucial role in the stabilization and function of numerous client proteins involved in cancer cell survival and proliferation. By inhibiting HSP90, NVP-HSP990 disrupts the chaperoning of these client proteins, leading to their degradation and ultimately inhibiting tumor growth. Its application is significant in preclinical studies aimed at understanding the mechanisms of HSP90 inhibition and evaluating its potential as a therapeutic target for various cancers, including breast, lung, and prostate cancers. Additionally, NVP-HSP990 is used in combination studies with other anticancer agents to explore synergistic effects and improve treatment efficacy. Its role in targeting multiple signaling pathways makes it a promising candidate for overcoming drug resistance in cancer therapy.
Product Specification:
| Test | Specification |
|---|---|
| Appearance | Solid |
| Purity (%) | 97.5-100 |
| Infrared Spectrum | Conforms To Structure |
| NMR | Conforms To Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 | 10-20 days | ฿4,600.00 |
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| 0.025 | 10-20 days | ฿22,500.00 |
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NVP-HSP990
NVP-HSP990 is primarily utilized in the field of cancer research as a potent and selective inhibitor of heat shock protein 90 (HSP90). This protein plays a crucial role in the stabilization and function of numerous client proteins involved in cancer cell survival and proliferation. By inhibiting HSP90, NVP-HSP990 disrupts the chaperoning of these client proteins, leading to their degradation and ultimately inhibiting tumor growth. Its application is significant in preclinical studies aimed at understanding the mechanisms of HSP90 inhibition and evaluating its potential as a therapeutic target for various cancers, including breast, lung, and prostate cancers. Additionally, NVP-HSP990 is used in combination studies with other anticancer agents to explore synergistic effects and improve treatment efficacy. Its role in targeting multiple signaling pathways makes it a promising candidate for overcoming drug resistance in cancer therapy.
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| Stable in pH range | - |
| Solubility | - |
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