IDH-305

≥98%

  • Product Code: 100923
  CAS:    1628805-46-8
Molecular Weight: 490.45 g./mol Molecular Formula: C₂₃H₂₂F₄N₆O₂
EC Number: MDL Number:
Melting Point: Boiling Point:
Density: Storage Condition: 2-8℃
Product Description: IDH-305 is primarily used in the field of oncology, specifically targeting cancers associated with mutations in the IDH1 gene. It functions as an inhibitor of the mutant IDH1 enzyme, which plays a role in the abnormal production of 2-hydroxyglutarate (2-HG), a metabolite that contributes to tumor growth. By blocking this enzyme, IDH-305 helps to normalize cellular metabolism and inhibit the progression of certain cancers, such as acute myeloid leukemia (AML) and cholangiocarcinoma. Its application is particularly significant in patients with IDH1-mutated tumors, offering a targeted therapeutic approach that can improve outcomes and reduce the side effects associated with conventional chemotherapy. Ongoing research continues to explore its potential in other IDH1-mutated cancers and combination therapies.
Product Specification:
Test Specification
Appearance White To Off-White Powder To Solid
Purity (%) 97.5-100
Infrared Spectrum Conforms To Structure
NMR Conforms To Structure
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.001 10-20 days ฿9,980.00
+
-
0.005 10-20 days ฿27,670.00
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-
IDH-305
IDH-305 is primarily used in the field of oncology, specifically targeting cancers associated with mutations in the IDH1 gene. It functions as an inhibitor of the mutant IDH1 enzyme, which plays a role in the abnormal production of 2-hydroxyglutarate (2-HG), a metabolite that contributes to tumor growth. By blocking this enzyme, IDH-305 helps to normalize cellular metabolism and inhibit the progression of certain cancers, such as acute myeloid leukemia (AML) and cholangiocarcinoma. Its application is particularly significant in patients with IDH1-mutated tumors, offering a targeted therapeutic approach that can improve outcomes and reduce the side effects associated with conventional chemotherapy. Ongoing research continues to explore its potential in other IDH1-mutated cancers and combination therapies.
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