Ingliforib
≥99%
- Product Code: 100996
CAS:
186392-65-4
| Molecular Weight: | 457.91 g./mol | Molecular Formula: | C₂₃H₂₄ClN₃O₅ |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8℃ |
Product Description:
Ingliforib is primarily investigated for its potential therapeutic applications in the treatment of cancer. It functions as an inhibitor of the enzyme geranylgeranyltransferase I (GGTase-I), which plays a crucial role in the post-translational modification of proteins involved in cell signaling and growth. By inhibiting GGTase-I, Ingliforib disrupts the activation of certain oncogenic proteins, particularly those in the Ras family, which are often implicated in uncontrolled cell proliferation and tumor growth. This mechanism makes it a promising candidate for targeting cancers driven by Ras mutations or other GGTase-I-dependent pathways. Research is ongoing to evaluate its efficacy, safety, and potential use in combination with other anticancer therapies.
Product Specification:
| Test | Specification |
|---|---|
| Appearance | Light Yellow To Yellow Solid |
| Purity (%) | 98.5 |
| Infrared Spectrum | Conforms To Structure |
| NMR | Conforms To Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 | 10-20 days | ฿46,170.00 |
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| 0.010 | 10-20 days | ฿76,950.00 |
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Ingliforib
Ingliforib is primarily investigated for its potential therapeutic applications in the treatment of cancer. It functions as an inhibitor of the enzyme geranylgeranyltransferase I (GGTase-I), which plays a crucial role in the post-translational modification of proteins involved in cell signaling and growth. By inhibiting GGTase-I, Ingliforib disrupts the activation of certain oncogenic proteins, particularly those in the Ras family, which are often implicated in uncontrolled cell proliferation and tumor growth. This mechanism makes it a promising candidate for targeting cancers driven by Ras mutations or other GGTase-I-dependent pathways. Research is ongoing to evaluate its efficacy, safety, and potential use in combination with other anticancer therapies.
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