SCH66336
99%
- Product Code: 101268
CAS:
193275-84-2
Molecular Weight: | 638.8200000000001 g./mol | Molecular Formula: | C₂₇H₃₁Br₂ClN₄O₂ |
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EC Number: | MDL Number: | MFCD06795138 | |
Melting Point: | Boiling Point: | ||
Density: | Storage Condition: | -20℃ |
Product Description:
SCH66336 is primarily used in cancer research as a potent and selective inhibitor of farnesyltransferase. This enzyme plays a critical role in the post-translational modification of proteins, including Ras proteins, which are often mutated in various cancers. By inhibiting farnesyltransferase, SCH66336 disrupts the activation of Ras signaling pathways, thereby inhibiting the proliferation and survival of cancer cells. It has been studied in preclinical and clinical trials for its potential therapeutic effects in treating solid tumors and hematologic malignancies. Additionally, SCH66336 has been explored for its ability to enhance the efficacy of other anticancer therapies when used in combination treatments. Its application extends to studying the molecular mechanisms of Ras-driven cancers and developing targeted cancer therapies.
Product Specification:
Test | Specification |
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Appearance | White To Beige Powder |
Purity (%) | 98.5-100 |
Infrared Spectrum | Conforms To Structure |
NMR | Conforms To Structure |
Sizes / Availability / Pricing:
Size (g) | Availability | Price | Quantity |
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0.001 | 10-20 days | ฿3,650.00 |
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0.005 | 10-20 days | ฿8,830.00 |
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0.025 | 10-20 days | ฿22,070.00 |
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SCH66336
SCH66336 is primarily used in cancer research as a potent and selective inhibitor of farnesyltransferase. This enzyme plays a critical role in the post-translational modification of proteins, including Ras proteins, which are often mutated in various cancers. By inhibiting farnesyltransferase, SCH66336 disrupts the activation of Ras signaling pathways, thereby inhibiting the proliferation and survival of cancer cells. It has been studied in preclinical and clinical trials for its potential therapeutic effects in treating solid tumors and hematologic malignancies. Additionally, SCH66336 has been explored for its ability to enhance the efficacy of other anticancer therapies when used in combination treatments. Its application extends to studying the molecular mechanisms of Ras-driven cancers and developing targeted cancer therapies.
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