LOXO-292

99%

  • Product Code: 101280
  CAS:    2222755-14-6
Molecular Weight: 553.61 g./mol Molecular Formula: C₂₉H₃₁N₉O₃
EC Number: MDL Number:
Melting Point: Boiling Point:
Density: Storage Condition: 2-8℃
Product Description: LOXO-292, also known as Selpercatinib, is primarily used in the treatment of certain types of cancer that are driven by specific genetic alterations. It is particularly effective in targeting cancers with RET gene mutations or fusions, which are often found in non-small cell lung cancer (NSCLC), medullary thyroid cancer (MTC), and other thyroid cancers. By inhibiting the RET protein, LOXO-292 helps to block the signaling pathways that promote cancer cell growth and survival. This targeted therapy offers a more precise approach compared to traditional chemotherapy, often resulting in fewer side effects and improved outcomes for patients with RET-altered cancers. It is typically administered orally, making it convenient for long-term treatment regimens. Clinical trials have demonstrated its efficacy in shrinking tumors and improving progression-free survival in patients with advanced or metastatic RET-driven cancers.
Product Specification:
Test Specification
Appearance White Solid
Purity (%) 98.5-100
Infrared Spectrum Conforms To Structure
NMR Conforms To Structure
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.100 10-20 days ฿9,500.00
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0.250 10-20 days ฿19,990.00
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LOXO-292
LOXO-292, also known as Selpercatinib, is primarily used in the treatment of certain types of cancer that are driven by specific genetic alterations. It is particularly effective in targeting cancers with RET gene mutations or fusions, which are often found in non-small cell lung cancer (NSCLC), medullary thyroid cancer (MTC), and other thyroid cancers. By inhibiting the RET protein, LOXO-292 helps to block the signaling pathways that promote cancer cell growth and survival. This targeted therapy offers a more precise approach compared to traditional chemotherapy, often resulting in fewer side effects and improved outcomes for patients with RET-altered cancers. It is typically administered orally, making it convenient for long-term treatment regimens. Clinical trials have demonstrated its efficacy in shrinking tumors and improving progression-free survival in patients with advanced or metastatic RET-driven cancers.
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